Function to Identify Network Regulators from Directed Networks

Identifies network un-weighted regulators from directed networks

Usage

regulatorAnalysis.directed(adj, G, h = 3, FDR = 0.05)

Arguments

adj

Required. An n x n weighted upper triangular adjacency in the matrix class format.

G

Required. A named vector of node scores.

h

Optional. Neighborhood search distance (h nodes away from current node) (Default = 3)

FDR

Optional. Adjusted pvalue cutoff for regulator selection. (Default = 0.05)

Value

scores = n x 5 dimensional data frame with columns giving neighborhood based score, adjusted pvalue, whether a gene is regulator/global regulator.