Function to Identify Network Regulators from Undirected Weighted Networks

Identifies network un-weighted regulators from Weighted undirected networks

Usage

regulatorAnalysis.undirected_weighted(adj, G, h = 3, n = 100, FDR = 0.05)

Arguments

adj

Required. An n x n weighted upper triangular adjacency in the matrix class format.

G

Required. A named vector of node scores.

h

Optional. Neighborhood search distance (h nodes away from current node) (Default = 3)

n

Optional. number of permuations to run. (Default = 100)

FDR

Optional. Adjusted pvalue cutoff for regulator selection. (Default = 0.05)

Value

scores = n x 4 dimensional list with columns giving neighborhood based score, adjusted pvalue, whether a gene is regulator/global regulator.