Normalize counts by CQN. By providing a biomart object, the systematic effect of GC content is removed and gene length (in bp) variation is accounted for. Genes with missing GC content or gene lengths will be removed from the counts matrix.

cqn(filtered_counts, biomart_results)

Arguments

filtered_counts

A counts data frame with genes removed that have low expression.

biomart_results

Output of "sageseqr::get_biomart()". Gene Ids are stored as rownames.