All functions

association_statistic_for_factors()

Compute the association statistic for factor variables

association_statistics_for_both()

Find intraclass correlation (ICC) between factor and continuous covariates

biomart_obj()

Get available Ensembl dataset

biomart_stats()

Get Gene Length and GC: biomart

boxplot_vars()

Explore metadata by variable.

build_formula()

Formula Builder

check_mismatch()

Check for consistent identifiers

clean_covariates()

Create covariate matrix from tidy metadata data frame.

coerce_continuous()

Coerce objects to type numeric.

coerce_factors()

Coerce objects to type factors.

collapse_duplicate_hgnc_symbol()

Duplicate HGNC

complete_path()

Create complete URL to Synapse entity

compute_residuals()

Compute residualized counts matrix

conditional_plot_sexcheck()

Conditionally wrap plot_sexcheck for targets

convert_geneids()

Get gene Ids

correlate_and_plot()

Calculate correlation between covariates and principal components (PCs)

cqn()

Conditional Quantile Normalization (CQN)

differential_expression()

Differential Expression with Dream

dropped_genes()

Dropped Genes Finder

filter_genes()

Filter genes

get_association_statistics()

Visualize relationship between variables

get_biomart()

Get Ensembl biomaRt object

get_data()

Detect file type and download data

gtf_stats()

Get Gene Length and GC: GTF/Fasta

identify_outliers()

Explore samples that are outliers

parse_counts()

Subset counts data frame

plot_coexpression()

Co-expression histogram generation

plot_pcs_with_covariates()

Explore relationship between principal components (PCs) and covariates

plot_sexcheck()

Explore metadata by gene expression on the sex chromosomes.

plot_sexcheck_pca()

Explore metadata by gene expression on the sex chromosomes (PCA)

plot_volcano()

Volcano plot differential expression results'

prepare_results()

Prepare output

provenance_helper()

Provenance helper

run_pca()

Principal Component Analysis (PCA) of samples

run_pca_and_plot_correlations()

Compute principal component analysis (PCA) and plot correlations

simple_filter()

Filter genes with low expression

start_de()

Initialize differential expression analysis workflow

stepwise_regression()

Stepwise Regression

store_results()

Store output to Synapse

summarize_biotypes()

Summarize Biotypes

threshold_fdr()

Apply false discovery rate (FDR) threshold to correlation matrix.

wrap_de()

Wrapper for Differential Expression Analysis